Active Substance: Anastrozole
Brand: Anastra Zeneca
Packaging: 30*1mg tablets/box
Anastrozole (aromatase inhibitor) is used in sports to reduce the side effects of the abuse of anabolic steroids.
Arimidex by AstraZeneca
Anastrozole, more commonly known name with its trade name of Arimidex, is a non-steroidal aromatase inhibitor (AI) drug. It was originally manufactured and approved in 1995 in the USA to help with the treatment of breast cancer. It was usually used after surgery, and was used for metastasis in women. Due to the fact that breast cancer could be aggravated by the increase of estrogen levels, Anastrozole was mainly used to help block the production of the hormone estrogen.
Use and Benefits of Anastrozole (Arimidex) in Bodybuilding
When a bodybuilder is on a steroid cycle, the use of certain anabolic androgenic compound could aromatize into estrogen. Among the compounds that would cause this are usually the ones with testosterone esters such as Boldenone, deca durabolin, dianabol, Enanthate and cypionate. On a cycle with one of these compounds, it is highly advisable for those who are prone to estrogenic side effects to use anastrozole or Arimidex as an ancillary to prevent side effects. One of the dreaded side effect is gynecomastia, and using an aromatase inhibitor like Arimidex could help prevent it. If it fully develops, only surgery can remove it. Prevention is better than cure.
Another side effect that can be avoided with the use of Anastrozole during a cycle is water retention. Water retention makes the body looks soft, rounded and bloated, and it could make a person to appear as if he was fat. Carrying unnecessary water weight will also be stressful to the body and might cause the lipid levels to spike. Other side effects that can be avoided with an aromatase inhibitor are loss of libido, high estrogen levels, fatigue, heart strain and high blood pressure.
However, keep in mind that if Anastrozole is abused, it could cause over-inhibition of estrogen, causing the levels in the body to drop way below normal values. This could lead to dangerous conditions such as depression, loss of energy, low libido and even erectile dysfunction.
Advantages of Anastrozole (Arimidex) as an Aromatase Inhibitor
Anastrozole is considered to be more effective compared to a SERM like Tamoxifen (Nolvadex). This is because it basically tackles the root of the problem, which is estrogen. It stops the production of estrogen. SERMs on the other hand binds to the estrogen receptors. While it does help, but there will be free estrogen floating in the body.
Compared to other Aromatase Inhibitor like Letrozole, Anastrozole is less harsh to the body and has significantly lower side effects, if any. While it is a mild aromatase inhibitor, it however does not destroy estrogen as aggressive as letrozole. It is considered to be the best aromatase inhibitor to be used on cycle to help prevent estrogenic side effects, and other should only be considered if there is no access to anastrozole.
Side Effects of Anastrozole (Arimidex)
The best thing about Anastrozole or Arimidex is the fact that side effects barely exists! There were studies that report the use of Anastrozole long term could cause weakness in bones in women. Keep in mind though that this is due to prolonged usage, up to years.
The average dosage of Anastrozole differs from one person to another, and this depends mainly on individual tolerance to the drug. It is important to run blood work when you are using Anastrozole to find out the ideal dosage for you. Always start conservative, around half a milligram every other day. Do blood work and adjust as needed. Most bodybuilders usually do not use Aromatase Inhibitors on cycle, however they will have it on hand just in case of any signs of estrogenic side effects that might arise.
It is totally up to individual preferences, however it is advisable to run it anyways, because once water retention or gynecomastia happens, it would be difficult to reverse these negative effects. As a rule of thumb, the general dosage is at 0.5 mg per day or every other day – do your blood work and find what the ideal dosage is for you! The dosage of Anastrozole is steroid dose dependent as well.