Exemestane by Actavis
Exemestane is one of the aromatase inhibitors of the third Generation and was developed as any other aromatase inhibitor for the treatment of estrogen- induced breast cancer in women.
Unlike older aromatase inhibitors exemestan docked firmly to the aromatase enzyme and this may disable permanently so . This connection can be released again , so that the aromatase enzyme is then re- activated .
In bodybuilding exemestan finds its application to the side-effects of anabolic and androgenic steroids Down to suppress . The flavoring by anabolic steroid abuse are bound by the drug exemestan for the most part .
Exemestane contains a very efficient aromatase . The activity of the enzyme aromatase is suppressed by up to 98 %, which means a reduction in the estrogen levels by 85 %. In comparison, the reduction in estrogen aromatase inhibitors such as anastrozole is at or letrozole in just under 80 %. For this reason, exemestan is the most valued among bodybuilders aromatase .
In this context, is to note that estrogen also has some anabolic effect and a strong reduction in estrogen levels through the use of aromatase inhibitors such as exemestan during use of anabolic androgenic steroids can result in reduced gains in muscle mass .
Side effects :
Hot flashes, nausea, fatigue, sweating, headache, insomnia, depression, decrease in lymphocytes, thrombocytopenia, leukopenia, elevation of liver enzymes, hypertrichosis, hair loss, hoarseness, acne
Application / dosage :
In bodybuilding, the half a tablet (12.5 mg exemestane) is usually used every day, or every 2 days one tablet ( 25mg exemestane) . in the last phase of a pre-contest bodybuilders take some daily 25mg exemestane .
Optimal is a intake after a high fat meal, because as the bioavailability can be increased by up to 40 percent. Until when taking exemestane stable blood levels are reached , passing by the manufacturer about a week.