Prop by Titan Healthcare

Testosterone Propionate is an injectable dosage form of testosterone dissolved in oil, in which the testosterone molecule has been combined with a propionate ester. Of all esters used for the esterification of testosterone, the propionate is esters with the shortest esters, which is also reflected in the short duration of action of Prop. It is often read that testosterone propionate is the testosterone with the shortest ester, but this is not entirely true, as the acetate ester of testosterone acetate is one carbon shorter. However, testosterone acetate plays no significant role except in a few testosterone combination products in the field of bodybuilding. The therapeutic use of testosterone propionate includes testosterone substitution in hypogonadism (testicular hypofunction), induction of puberty in boys with delayed onset of puberty, treatment of aplastic anemia (red blood cell failure) and concomitant therapy in advanced breast cancer.

The main difference between testosterone prop and longer testosterone esters such as testosterone enanthate or testosterone cypionate is the length of the ester attached to the testosterone molecule. Due to the significantly shorter ester testosterone propionate has only a working time of 2 – 3 days, which brings advantages and disadvantages compared to longer testosterone esters. The advantage of the short ester is a faster release of the testosterone and a higher testosterone content per milligram of active ingredient, since the ester is included in the amount of active ingredient (100 mg of testosterone propionate contains about 84 mg of testosterone, whereas 100 mg of testosterone enanthate only 72 mg of testosterone contain). The main disadvantage of the short reaction time is the short injection intervals necessary to achieve reasonably stable drug levels in the body. In practice, it can be observed that testosterone propionate is particularly popular with athletes who have to undergo doping tests, because testosterone propionate is rapidly broken down by the body due to its short half-life, and thus a negative doping test is expected soon after weaning is.

On the Internet and in many areas of steroid literature, it is often said that testosterone propionate has fewer side effects than longer testosterone esters such as testosterone enanthate and cypionate. In this context, lower water retention is particularly frequently reported. However, this statement is not entirely correct. If you take a closer look at the exact biochemical processes in the body, then you will see that esterified testosterone can only become biologically active if the ester has been separated from the testosterone molecule and it is present in free form. Thus, the active drug molecule is present in both Prop and all other testosterone esters, e.g. Testosterone enantate identical and therefore must also have an identical effect. However, the observed lower side effects and water retention can be attributed to two other factors. On the one hand, testosterone is often used at a lower weekly dosage because of the usually smaller amount of active ingredient per milliliter of injection solution, and secondly, Prop has lower peak values ​​of testosterone due to its shorter half-life and lack of active ingredient accumulation than e.g. Testosterone enanthate is the case. In this context, it should be mentioned that there are indications that the degree of estrogen-related side effects, which include water retention, is also influenced by such peak values ​​of the testosterone level.

In the field of bodybuilding, it can be observed that Prop is mainly used during dieting and competition preparation. The reason for this is once again the short half-life, which allows a more easily controlled testosterone level, which can reduce unwanted water retention. In practice, one can observe that testosterone propionate for this purpose with other short-acting and / or non-aromatizing injectable steroids such as trenbolone acetate, drostanolone propionate (Masteron), metenolone (Primobolan) and / or injectable stanozolol (Winstrol Depot) as well as non-flavoring oral Steroids such as Stanozolol (Winstrol), Fluoxymesteron and / or Oxandrolone (Anavar) is combined. Furthermore, it can often be observed in practice that accompanying aromatase inhibitors or mesterolone (Proviron) are used in order to reduce estrogen-related side effects and to achieve a harder appearance.

When it comes to mass building, it can be observed in practice that longer testosterone esters such as testosterone enanthate or testosterone cypionate are usually preferred to testosterone propionate because of the longer injection intervals, but this does not mean that testosterone propionate is not also used for this purpose comes. In practice, it can often be observed that testosterone propionate is used at the beginning of the mass phase as a kind of “kickstarter”, because with its help faster high levels of active ingredient can be achieved than with longer testosterone esters.

Prop dosages used in the medical field are 50 mg every 4 to 5 days for the purpose of hormone replacement with testicular hypofunction and between 300 and 1000 mg per week divided into 2 to 3 injections for the treatment of aplastic anemia (1). In the area of ​​bodybuilding dosages of 50 – 100 mg can be observed in practice every other day or every other day. The short injection intervals observed are based on the fact that testosterone levels fall sharply as early as the third day after injection (2). Testosterone propionate users often report that irritation and irritation at the injection site is more common than with other testosterone esters, which can be particularly severe if the injection site is not cycled.

In practice, it can be observed that testosterone propionate is the only testosterone ester that is also used by some women, because on the one hand the testosterone levels are easier to control and on the other hand the drug is quickly discontinued at the first sign of androgenic side effects due to the short half-life can, which is not possible with longer testosterone esters. The dosage observed in women in practice is between 25 and 50 mg every 5 to 7 days, with the observed duration of intake usually being in the range of a few weeks, with signs of miscarriage.