Active Substance: Mesterolone
Proviron is a very needful drug for On- and Post Cycle Therapy to prevent side effects of anabolic steroids
Proviron by Bayer
Mesterolone is more fondly known by its brand name, Proviron, and it is an orally administered derivative of dihydrotestosterone (DHT) androgenic hormone. Naturally, 5% of the body’s total testosterone is converted into the form of the powerful androgen DHT when it goes through the 5-alpha reduction. DHT is a strong androgen hormone and sex hormone. DHT is an important sex hormone that is crucial to the development of the male genitals of adults, and it is also a primary androgen in the hair follicles and prostate. Proviron can be considered to be one of the purest form of DHT steroid available today. With a potent compound like Mesterolone, the issues of estrogen aromatization will not be a main concern in anabolic androgenic steroid cycles.
Medically, Mesterolone was formulated and manufactured as an aid in treating anxiety and depression, as well as to help boost libido to help patients with lack of sex drive. Those with psychological conditions such as dysthymia, unipolar and bipolar would benefit from the use of Mesterolone. It is also normally prescribed by specialists to men who are bothered by lack of libido. It is also used as a kick-start in full testosterone replacement therapy (TRT)
The Use and Benefits of Mesterolone (Proviron) in Bodybuilding
Originally back then, Mesterolone or Proviron was popularly used as an anti-estrogen agent due to its ability and highly efficient capacity to bind to the aromatase enzyme, this would mean that those who are cycling with anabolic steroids who cannot get their hands on Aromatase Inhibitor (AI) could use Mesterolone instead.
Some bodybuilders would use Mesterolone as part of their post cycle therapy plan, but there are studies that have reported that Mesterolone does supress luteinizing hormone (LH) – on rare occasions. Because of this, researchers suggests that for some, Mesterolone of Proviron on high dosage might disrupt the recovery process of the pituitary gland after an anabolic androgenic steroid cycle. There are bodybuilders who would vouch against this, and that it could be a good ancillary during post cycle therapy or a bridge – and this is absolutely up for debate. There are studies that contradicts other studies.
However today, with the availability of letrozole, arimidex and aromasin, Mesterolone is no longer an effective aromatase inhibitor and considered to be obsolete as an anti-estrogen. The likes of aromasin, arimidex and letrozole is the safest ancillary to use during a post cycle therapy, and it does not at all, supress your HPTA. Mesterolone might do on some who are prone to it – on rare occasions, though it should not.
But this does not at all mean that Mesterolone or Proviron is not useful anymore. It is extremely useful on cycle instead of post cycle therapy, especially when you are on an aromatizing compound such as equipoise, nandrolones, testosterone or dianabol. Bodybuilders who use Proviron on cycle report of havinga more harder look, added vascularity and very little puffiness as compared to cycling without Mesterolone.
Another main benefit of Mesterolone is its ability to effectively bind to sex hormone binding globulin (SHBG), which is the type of hormone in the body that is responsible for reducing the levels of free testosterone floating in the body. This is also one of the reason why some bodybuilders would vouch for the use of Mesterolone during PCT. Those who are professionally competing love mesterolone’s hardening effect. This is because Mesterolone is 5-alpha reduced, which will not form estrogen, resulting in a drier, harder look.
Due to it not being anabolic, it is pretty useless to be used alone by a bodybuilder. However, it Mesterolone is stacked with other wet compounds, it could improve its results by balancing hardness and size for your muscles. For example, in a stack of testosterone, dianabol and 25 mg of Proviron a day, one would expect to not get the typical puffy and bloated muscle look like it should, without Mesterolone. It is also safe to be stacked with other orals since it is a non c17-alpha-alkalyted compound.
Those who are prone to male pattern baldness might experience hair loss when on Mesterolone.
Half Life and Dosage
25 mg to 75 mg per day is the typical dosage of Mesterolone. The detection time is around 5 to 6 weeks after the last dosage.